OBC (2016) : “Stereoelectronic effects in the reaction of aromatic substrates catalysed by Halomonas elongata transaminase and its mutants”
Well done for Martina e Matteo, the work of the last few months has been successfully accepted by OBC. New paper in our library: Stereoelectronic effects in the reaction of aromatic substrates catalysed by Halomonas elongata transaminase and its mutants. (doi:10.1039/C6OB01629D)
Green Chemistry (2017) : “Continuous flow biocatalysis: production and in-line purification of amines by immobilised transaminase from Halomonas elongata”
Great achievement for the group! Matteo, Martina and Jenni, together with our collaborators in Milan (Prof. Molinari and Dr. Tamborini) are celebrating a very nice paper on flow chemistry using our transaminase from Halomonas. Well done! The paper “Continuous flow biocatalysis: production and in-line purification of amines by immobilised transaminase from Halomonas elongata” is published […]
Amino Acids (2017): Stabilization of Angiotensin-(1–7) by key substitution with a cyclic non-natural amino acid
Well done to Anita! Her work finally rewarded! This paper was the result of our collaborative work with Prof. Gallagher at Wake Forest University in North Carolina and the major stabilising effect of incorporating our non natural cyclic amino acid into the Angiotensin sequence, without loosing its anti proliferative properties is a significant step forward […]
Chemistry Today (2017): Mini-review “Biocatalysis takes to flow”
F. Paradisi “Biocatalysis takes to flow” Chemistry Today, 2017, 35, 2
ChemCatChem (2017): Highly Efficient Oxidation of Amines to Aldehydes with Flow-based Biocatalysis
Another great achievement for the group. This paper was chosen for the front cover of the journal, stay tuned to see how it looks like! The article is already available online https://doi.org/10.1002/cctc.201701147
Trends in Biotechnology (2018): “Flow Bioreactors as Complementary Tools for Biocatalytic Process Intensification”
We have a nice review which just went online, a mammoth effort between Milan, Lisbon, and Nottingham https://doi.org/10.1016/j.tibtech.2017.09.005
OBC (2017): “Extreme halophilic alcohol dehydrogenase mediated highly efficient syntheses of enantiopure aromatic alcohols”
I am delighted that Diya’s final paper has now been accepted! Diya went back to Jordan after finishing his PhD in the group and now runs his own lab at the Royal Scientific Society. He secured funding to finish a very interesting project using the halophilic HvADH2 from H. volcanii to prepare a large range […]
PlosOne (2017): “Engineering substrate promiscuity in halophilic alcohol dehydrogenase (HvADH2) by in silico design”
Great work for Jenni and Larah who successfully published a nice piece of research in Plos One. This was a collaborations between our group and the group of Prof. Loredano Pollegioni in Milan, so massive thanks to them also! PlosOne is open access, you can read the article without a subscription to the journal. Cassidy […]
Catalysts (2018): “Genetically Fused T4L Acts as a Shield in Covalent Enzyme Immobilisation Enhancing the Rescued Activity”
Well done to Matteo, David (first paper!) and Martina for this paper. It was an invited publication for a special issue of the journals Catalysts on “Immobilized Biocatalysts”. You can read the paper here: http://www.mdpi.com/2073-4344/8/1/40/pdf
Molecular Biotechnology (2018): “Haloquadratum walsbyi yields a versatile, NAD+/NADP+ dual affinity, thermostable, alcohol dehydrogenase (HwADH)”
The discovery of new sources of biocatalysts is challenging and often not that rewarding. Delighted for Jenni’s work on this new ADH from a very unusual archaeon which is virtually impossible to culture in the lab. Molecular Biotechnology https://doi.org/10.1007/s12033-018-0083-6